Dr. Arlene Chapman, MD

• Nephrology

• Internal Medicine

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• Georgetown University

  Fellowship Hospital, 1988

• Georgetown University

  Residency Hospital, 1986

• Mcmaster University / Faculty Of Health Sciences

  Medical School, 1983

• HypertensiveAPOL1risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers, 2019-09-18

• Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics, 2017-11-22

• Image texture features predict renal function decline in patients with Autosomal Dominant Polycystic Kidney Disease, 2017-05-20

• Tolvaptan in ADPKD Patients With Very Low Kidney Function, 2021-06-09

• Race specific comparisons of antihypertensive and metabolic effects of hydrochlorothiazide and chlorthalidone, 2021-01-09

• Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients, 2021-09-21

• The STAGED-PKD 2-Stage Adaptive Study With a Patient Enrichment Strategy and Treatment Effect Modeling for Improved Study Design Efficiency in Patients With ADPKD, 2022-08-27

• Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy, 2018-11-10

• A GENETIC RESPONSE SCORE FOR HYDROCHLOROTHIAZIDE USE: INSIGHTS FROM GENOMICS AND METABOLOMICS INTEGRATION, 2016-07-05

• Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials, 2018-01-03

• Determinants of Progression in Early Autosomal Dominant Polycystic Kidney Disease - Is it Blood Pressure or Renin-Angiotensin-Aldosterone-System Blockade?, 2018-04-10

• Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response, 2019-11-21

• Closeout of the HALT-PKD Trials, 2015-07-29

• Pharmacogenomics of Hypertension in CKD: The CKD-PGX Study, 2022-02-24

• Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease, 2019-03-09

• Protein kinase Ca deletion causes hypotension and decreased vascular contractility, 2018-01-24

• Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients, 2022-08-24

• Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study, 2018-02-27

• Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated with Thiazide Diuretics Blood Pressure Response, 2017-01-06

• Performance of the Chronic Kidney Disease Epidemiology Collaboration equation to estimate glomerular filtration rate in a longitudinal study of Autosomal Dominant Polycystic Kidney Disease, 2016-12-24

• Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies, 2019-02-10

• Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies, 2018-06-20

• Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach, 2016-07-13

• Targeted Sequencing Identifies Missense variant in theBEST3gene associated with Antihypertensive Response to Hydrochlorothiazide, 2018-09-10

• Effect of statin therapy on the progression of autosomal dominant polycystic kidney disease. A secondary analysis of the HALT PKD trials, 2017-11-02

• Pharmacogenomic studies of hypertension: paving the way for personalized antihypertensive treatment, 2018-01-03

• Blood Pressure Response to Metoprolol and Chlorthalidone in Hypertensive European and African Americans, 2017-09-21