Dr. Christopher Hughes, MD

• Critical Care Medicine

• Anesthesiology

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• Indiana University / Bloomington

  Medical School, 2005

• In the ICU - Delirium Post Cardiac Arrest, 2019-07-20

• Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients, 2019-12-19

• Balanced Crystalloids versus Saline in Critically Ill Adults, 2018-05-17

• Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study, 2019-05-23

• Relationships between Markers of Neurologic and Endothelial Injury during Critical Illness and Long-Term Cognitive Impairment and Disability, 2018-03-09

• Association between cholinesterase activity and critical illness brain dysfunction, 2022-12-06

• Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis, 2021-02-02

• Pharmacologic Management of Intensive Care Unit Delirium: Clinical Prescribing Practices and Outcomes in Over 8500 Patient Encounters, 2021-09-01

• The genome-wide DNA methylation profiles among neurosurgery patients with and without post-operative delirium, 2022-11-17

• DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium, 2021-12-09

• Co-occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness, 2018-04-24

• Prevalence and Course of Frailty in Survivors of Critical Illness, 2021-02-13

• Epidemiology and risk factors for delirium across hospital settings, 2013-02-12

• Targeting light versus deep sedation for patients receiving mechanical ventilation, 2018-10-19

• Design and Rationale of the Sevoflurane for Sedation in Acute Respiratory Distress Syndrome (SESAR) Randomized Controlled Trial, 2022-05-16

• American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention, 2020-06-29

• Motoric Subtypes of Delirium and Long-Term Functional and Mental Health Outcomes in Adults after Critical Illness, 2021-05-01

• Sedative Plasma Concentrations and Delirium Risk in Critical Illness, 2018-01-24

• Response to: "Motoric Subtypes of Delirium: Not associated with Long-Term Outcomes in Adults After Critical Illness?”, 2021-12-01

• Association of Neuronal Repair Biomarkers with Delirium among Survivors of Critical Illness, 2019-12-16

• Baseline Vulnerabilities May Play a Larger Role Than Depth of Anesthesia or Sedation in Postoperative Delirium, 2021-12-01

• Saline versus Balanced Crystalloids for Adults with Aneurysmal Subarachnoid Hemorrhage: A Subgroup Analysis of the SMART Trial, 2022-05-08

• Creation and Execution of a Novel Anesthesia Perioperative Care Service at a Veterans Affairs Hospital, 2023-05-05

• Association of Delirium during Critical Illness with Mortality: Multicenter Prospective Cohort Study, 2021-11-01

• Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness, 2018-03-09

• Association of Hypoactive and Hyperactive Delirium With Cognitive Function After Critical Illness, 2021-06-11

• The Attributable Mortality of Postoperative Bleeding Exceeds the Attributable Mortality of Postoperative Venous Thromboembolism, 2020-07-25