Dr. Dean Wong, MD

• Nuclear Medicine

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• The Johns Hopkins Hospital

  Fellowship Hospital, 1983

• Toronto General Hospital

  Residency Hospital, 1980

• Princess Margaret Hospital

  Residency Hospital, 1979

• Sunnybrook Medical Center

  Internship Hospital, 1978

• University Of Toronto, Fac Med

  Medical School, 1977

• Endocannabinoid system: potential novel targets for treatment of schizophrenia, 2012-12-07

• Cognitive reserve in midlife is not associated with amyloid-ß deposition in late-life, 2019-03-22

• Family history of alcoholism is related to increased D2/D3 receptor binding potential: a marker of resilience or risk?, 2015-09-29

• Remission of Gilles de la Tourette Syndrome after Heat-Induced Dehydration, 2018-06-13

• A multivariate nonlinear mixed effects model for longitudinal image analysis: Application to amyloid imaging, 2016-04-16

• Association of Smoking with Mu- Opioid Receptor Availability Before and During Naltrexone Blockade in Alcohol-Dependent Subjects, 2012-12-18

• Blood levels and dopamine transporter occupancy of orally administered methylphenidate in juvenile rhesus monkeys measured by high resolution PET, 2008-08-25

• Effect of STN DBS on vesicular monoamine transporter 2 and glucose metabolism in Parkinson's disease, 2019-04-16

• Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study, 2021-05-27

• The Role of Dopamine in Value-Based Attentional Orienting, 2016-02-11

• Ethnic disparities in pain processing among healthy adults: µ-opioid receptor binding potential as a putative mechanism, 2020-01-15

• History of Childhood Adversity is Positively Associated with Ventral Striatal Dopamine Responses to Amphetamine, 2014-01-22

• AnIn VivoEvaluation of Cerebral Cortical Amyloid with [18F]Flutemetamol Using Positron Emission Tomography Compared with Parietal Biopsy Samples in Living Normal Pressure Hydrocephalus Patients, 2014-02-20

• CSF Biomarkers and Its Associations with18F-AV133 Cerebral VMAT2 Binding in Parkinson's Disease-A Preliminary Report, 2016-10-20

• Association Between Serotonin Denervation and Resting-State Functional Connectivity in Mild Cognitive Impairment, 2017-04-05

• Dissociative changes in Bmaxand KDof dopamine D2/D3 receptors with aging observed in functional subdivisions of striatum: A revisit with an improved data analysis method, 2012-04-09

• Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome: A Pilot Study, 2021-03-11

• Fragile X Mental Retardation Protein and Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome: A Pilot Study, 2022-02-26

• The effect of ApoE e4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study, 2019-03-28

• GM1 Ganglioside in Parkinson's Disease: Pilot Study of Effects on Dopamine Transporter Binding, 2015-06-16

• Synthesis and Biological Evaluation of Novel Carbon-11 Labeled Pyridyl Ethers: Candidate Ligands for In Vivo Imaging of a4ß2 Nicotinic Acetylcholine Receptors (a4ß2-nAChRs) in the brain with Positron Emission Tomography, 2009-05-15

• Human Brain Imaging of a7 nAChR with [18F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy, 2017-02-18

• Brain Imaging of Cannabinoid Type I (CB1) Receptors in Women with Cannabis Use Disorder and Male and Female Healthy Controls, 2021-05-24

• The Associations between Left Ventricular structure, function, and Cerebral Amyloid: The ARIC-PET study, 2019-10-10

• Correction to: An open-label, positron emission tomography study of the striatal D2/D3receptor occupancy and pharmacokinetics of single-dose oral brexpiprazole in healthy participants, 2021-01-04

• ß-amyloid deposition is Associated with Gait variability in Usual Aging, 2018-02-06

• Linking Dopaminergic Reward Signals to the Development of Attentional Bias: A Positron Emission Tomographic Study, 2017-05-30

• Longitudinal patterns of ß-amyloid deposition in nondemented older adults, 2011-06-01

• The Relationship between naloxone-induced cortisol and delta opioid receptor availability in mesolimbic structures is disrupted in alcohol dependent subjects, 2012-01-20

• Midlife Adiposity predicts earlier onset of Alzheimer's dementia, neuropathology and presymptomatic cerebral amyloid accumulation, 2015-09-01

• Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study, 2018-02-12

• Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat hippocampus, 2020-04-08

• Development of a radioligand for imaging V1avasopressin receptors with PET, 2017-08-18

• Risky Decision-Making and Ventral Striatal Dopamine Responses to Amphetamine: A Positron Emission Tomography [11C] Raclopride Study in Healthy Adults, 2015-03-18

• Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study, 2021-03-12

• Temporal trajectory and progression score estimation from voxelwise longitudinal imaging measures: Application to amyloid imaging, 2015-09-25

• Dataset of quantitative structured office measurements of movements in the extremities, 2020-06-18

• Association between midlife vascular risk factors and estimated brain amyloid deposition, 2017-04-11

• Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference: a comorbidity model, 2011-02-17

• Deformation field correction for spatial normalization of PET images, 2015-06-30

• Reduced Expression of Cerebral Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome, 2020-11-24

• Correspondence betweenin vivo11C-PiB PET amyloid imaging andpost-mortem, region-matched assessment of plaques, 2012-08-05

• Diagnostic effectiveness of quantitative [18F]flutemetamol PET imaging for detection of fibrillar amyloid ß using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus, 2014-04-22

• Self-Reported Sleep and ß-Amyloid Deposition in Community-Dwelling Older Adults, 2013-12-01

• Deformation field correction for spatial normalization of PET images using a population-derived partial least squares model, 2014-10-23

• Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity A Translational Approach, 2018-09-18

• The Relationship between naloxone-induced cortisol and mu opioid receptor availability in mesolimbic structures is disrupted in alcohol dependent subjects, 2012-06-18

• The association between midlife lipid levels and late-life brain amyloid deposition, 2020-04-15

• In VivoImaging of Amyloid Deposition in Alzheimer's Disease using the Novel Radioligand [18F]AV-45 (Florbetapir F 18), 2011-02-28

• Molecular Imaging of Serotonin Degeneration in Mild Cognitive Impairment, 2017-05-13

• Performance assessment of a NaI(Tl) gamma counter for PET applications with methods for improved quantitative accuracy and greater standardization, 2015-05-06

• Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): Implications to manganese-induced parkinsonism, 2008-09-20

• Objectively Measured Sleep and ß-amyloid Burden in Older Adults: A Pilot Study, 2014-08-12

• An open-label, positron emission tomography study of the striatal D2/D3receptor occupancy and pharmacokinetics of single-dose oral brexpiprazole in healthy participants, 2020-11-16