Dr. John Chen, MD

• Neuroradiology

• Diagnostic Radiology

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• Massachusetts General Hospital

  Fellowship Hospital, 2005

• Massachusetts General Hospital

  Residency Hospital, 2004

• University Of Illinois Hospital

  Internship Hospital, 2000

• University Of Illinois College Of Medicine

  Medical School, 1999

• Incorporating algorithmic uncertainty into a clinical machine deep learning algorithm for urgent head CTs, 2023-03-13

• Induced Adult Neurogenesis plus BDNF Mimicks the Effects of Exercise on Cognition in an Alzheimer's Mouse Model, 2018-09-07

• Phf8loss confers resistance to depression-like and anxiety-like behaviors in mice, 2017-05-09

• Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice, 2013-04-24

• Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice, 2012-03-21

• Measuring Myeloperoxidase Activity in Biological Samples, 2013-07-05

• Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy, 2008-12-25

• Enzyme-Sensitive MR Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques, 2009-08-03

• Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability and toxicity, 2010-01-13

• A single reporter for targeted multimodal in vivo imaging, 2012-03-07

• Dynamic Biodistribution of Extracellular VesiclesIn VivoUsing a Multimodal Imaging Reporter, 2014-01-09

• Optimizing animal models of autoimmune encephalitis using active immunization, 2023-07-12

• Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors, 2014-05-05

• Stochastic Model ofTsc1Lesions in Mouse Brain, 2013-05-16

• Angiotensin II drives the production of tumor-promoting macrophages, 2013-01-17

• Surface biotinylation of cytotoxic T-lymphocytes forin vivotracking of tumor immunotherapy in murine models, 2016-10-08

• Highly Efficient Activatable MRI Probe to Sense Myeloperoxidase Activity, 2021-05-04

• Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease, 2017-01-16

• A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma, 2019-06-11

• Multimodal molecular imaging demonstrates myeloperoxidase regulation of matrix metalloproteinase activity in neuroinflammation, 2018-05-28

• Multimodal targeted high relaxivity thermosensitive liposome forin vivoimaging, 2015-11-27

• Enhanced in vivo imaging of metabolically biotinylated cell surface reporters, 2011-01-07

• Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging Molecular MRI of intracerebral inflammation, 2011-05-10

• Predicting the Severity and Prognosis of Trismus after Intensity-Modulated Radiation Therapy for Oral Cancer Patients by Magnetic Resonance Imaging, 2014-03-21

• The Relationship Between Serial [18F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice, 2014-07-17

• PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [18F]PBR06, 2013-07-09

• D-Mannose Slows Glioma Growth by Modulating Myeloperoxidase Activity, 2021-12-18

• Molecular MRI of myocardial peroxidase activity in ischemic injury reveals a chemical milieu incompatible with stem cell survival, 2016-01-27

• Optimal Brain MRI Protocol for New Neurological Complaint, 2014-10-24

• A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales, 2019-10-12

• Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction, 2023-03-16

• Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation, 2020-05-08

• Molecular immuno-imaging improves tumor detection in head and neck cancer, 2022-10-14

• Dynamic1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma, 2015-08-20

• Molecular imaging of macrophage enzyme activity in cardiac inflammation, 2014-02-18

• Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections, 2009-08-07