Dr. John Sfakianos, MD

• Urology

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• State University Of New York At Buffalo

  Medical School, 2007

• Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers, 2020-05-21

• Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing, 2021-04-09

• Pentafecta for Radical Nephroureterectomy in Patients with High-Risk Upper Tract Urothelial Carcinoma: A Proposal for Standardization of Quality Care Metrics, 2022-03-31

• Harnessing Natural Killer Cell Function for Genitourinary Cancers, 2020-09-02

• Comparison of Post-Radical Cystectomy Ileus Rates Using GIA-80 versus GIA-60 Intestinal Stapler Device, 2018-09-20

• TIM-3 and TIGIT are possible immune checkpoint targets in patients with bladder cancer, 2020-07-12

• Demographic and socioeconomic predictors of treatment delays, pathologic stage, and survival among patients with penile cancer: A report from the National Cancer Database, 2017-10-12

• Comparing Oncological and Perioperative Outcomes of Open versus Laparoscopic versus Robotic Radical Nephroureterectomy for the Treatment of Upper Tract Urothelial Carcinoma: A Multicenter, Multinational, Propensity Score-Matched Analysis, 2023-02-23

• Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome, 2018-01-23

• Tumor Heterogeneity and Consequences for Bladder Cancer Treatment, 2021-10-22

• Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition, 2016-05-10

• Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome, 2018-06-07

• Tumor Downstaging as an Intermediate Endpoint to Assess the Activity of Neoadjuvant Systemic Therapy in Patients With Muscle-Invasive Bladder Cancer, 2019-05-31

• Genomic Characterization of Upper Tract Urothelial Carcinoma, 2015-08-14

• The Evolving Clinical Management of Genitourinary Cancers Amid the COVID-19 Pandemic, 2021-09-27

• EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer, 2018-08-29

• Prospective Phase II Study to Evaluate Response to Two Induction Courses (12 intravesical instillations) of BCG Therapy for High-Risk Non-Muscle-Invasive Bladder Cancer, 2021-07-15

• Impact of Ureteroscopy Prior to Nephroureterectomy for Upper Tract Urothelial Carcinoma on Oncologic Outcomes, 2016-05-26

• NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer, 2022-09-12

• Prognostic value of lymph node yield during nephroureterectomy for upper tract urothelial carcinoma, 2016-12-05

• Genomic Biomarkers for the Prediction of Stage and Prognosis of Upper Tract Urothelial Carcinoma, 2016-01-14

• Genomic differences between black and white patients implicate a distinct immune response to papillary renal cell carcinoma, 2016-12-23

• Poor prognosis of bladder cancer patients with occult lymph node metastases treated with neoadjuvant chemotherapy, 2018-05-04

• Fibroblast Growth Factor Receptor 3 Alterations and Response to PD-1/PD-L1 Blockade in Patients with Metastatic Urothelial Cancer, 2019-07-01

• Genomic Profile of Urothelial Carcinoma of the Upper Tract from Ureteroscopic Biopsy: Feasibility and Validation Using Matched Radical Nephroureterectomy Specimens, 2018-02-01

• A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles, 2020-02-28

• Tumor Infiltrating Myeloid Cells Confer de novo Resistance to PD-L1 Blockade through EMT-stromal and Tgf-beta Dependent Mechanisms, 2022-11-03