Dr. Samuel Brown, MD

• Critical Care Medicine

• Pulmonary Disease

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Harvard University / School Of Psychology

  Medical School, 2001

• Central venous pressure and shock index predict lack of hemodynamic response to volume expansion in septic shock: A prospective, observational study?,??, 2012-10-17

• Association between unmet medication needs after hospital discharge and readmission or death among acute respiratory failure survivors: the addressing post-intensive care syndrome (APICS-01) multicenter prospective cohort study, 2022-01-07

• Understanding Patient Outcomes after Acute Respiratory Distress Syndrome: Identifying Subtypes of Physical, Cognitive, and Mental Health Outcomes, 2017-08-04

• Validation of the Infectious Disease Society of America/American Thoracic Society 2007 Guidelines for Severe Community-Acquired Pneumonia, 2009-09-16

• Systolic blood pressure variability in patients with early severe sepsis or septic shock: a prospective cohort study, 2017-06-17

• Long-term Implications of Abnormal Left Ventricular Strain during Sepsis, 2021-04-01

• Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS, 2019-12-27

• Multi-complexity measures of heart rate variability and the effect of vasopressor titration: a prospective cohort study of patients with septic shock, 2016-10-10

• Structure, process and annual intensive care unit mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study (USCIITG-CIOS), 2014-05-02

• Fluid Management With a Simplified Conservative Protocol for the Acute Respiratory Distress Syndrome*, 2015-06-05

• Coefficient of Variation of Coarsely Sampled Heart Rate Is Associated with Early Vasopressor Independence in Severe Sepsis and Septic Shock, 2014-02-26

• Erratum to: Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?, 2014-12-02

• At the X-Roads of Sex and Genetics in Pulmonary Arterial Hypertension, 2020-11-20

• Mortality, morbidity, and disease severity of patients with aspiration pneumonia, 2012-11-26

• Unanticipated critical findings on echocardiography in septic patients, 2020-04-02

• Order Substitutions and Education for Balanced Crystalloid Solution Use in an Integrated Health Care System and Association With Major Adverse Kidney Events Education for Balanced Crystalloid Solution Use and Association With Major Adverse Kidney Events, 2022-05-03

• Right and Left Heart Failure in Severe H1N1 Influenza A Infection, 2010-06-01

• Relative Bradycardia in Patients with Septic Shock Requiring Vasopressor Therapy, 2017-05-16

• Institution of an emergency department "swarming” care model and sepsis door-to-antibiotic time: A quasi-experimental retrospective analysis, 2020-05-05

• Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months, 2023-02-14

• Association of hospice utilization and publicly reported outcomes following hospitalization for pneumonia or heart failure: a retrospective cohort study, 2018-01-09

• Physician variation in time to antimicrobial treatment for septic patients presenting to the emergency department, 2017-03-18

• Prevalence, Characteristics, and Outcomes of Emergency Department Discharge Among Patients With Sepsis Prevalence, Characteristics, and Outcomes of ED Discharge Among Patients With Sepsis, 2022-02-10

• Simple scoring tool to estimate risk of hospitalization and mortality in ambulatory and emergency department patients with COVID-19, 2022-03-03

• Defining Severe Pneumonia, 2011-07-12

• Diastolic dysfunction and mortality in early severe sepsis and septic shock: a prospective, observational echocardiography study, 2012-05-04

• Preliminary Identification of Coping Profiles Relevant to Surrogate Decision Making in the ICU, 2016-11-11

• Associations among left ventricular systolic function, tachycardia, and cardiac preload in septic patients, 2017-02-17

• Postseptic Cognitive Impairment and Expression of APOE in Peripheral Blood: The Cognition After SepsiS (CASS) Observational Pilot Study, 2020-01-09

• Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial, 2018-08-13

• The peripheral blood transcriptome in septic cardiomyopathy: an observational, pilot study, 2019-10-24

• Humanizing the intensive care unit, 2019-01-28

• Concise Definitive Review: Focused Critical Care Echocardiography in the ICU, 2013-09-07

• Application of a simplified definition of diastolic function in severe sepsis and septic shock, 2016-08-04

• Influenza Vaccine Acceptance and Hesitancy Among Adults Hospitalized with Severe Acute Respiratory Illnesses, United States 2019-2020, 2021-08-07

• Authors' Reply to Letters to Editor re: "Physician variation in time to antimicrobial treatment for septic patients presenting to the emergency department”, 2017-09-17

• IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis, 2022-12-01

• Validation of the Intermountain patient perception of quality (PPQ) survey among survivors of an intensive care unit admission: a retrospective validation study, 2015-04-14

• Initial fractal exponent of heart-rate variability is associated with success of early resuscitation in patients with severe sepsis or septic shock: a prospective cohort study, 2013-08-17

• New-Onset Systemic Capillary Leak Syndrome in an Adult Patient with COVID-19, 2021-09-30

• Phenotypic clusters within sepsis-associated multiple organ dysfunction syndrome, 2015-04-08

• Long-term Outcomes after Severe Shock, 2014-10-17

• Prospective evaluation of an automated method to identify patients with severe sepsis or septic shock in the emergency department, 2016-08-22

• Predictors of 6 Month Health Utility Outcomes in Survivors of Acute Respiratory Distress Syndrome, 2016-07-20

• Non-linear imputation of PaO2/FIO2from SpO2/FIO2among mechanically ventilated patients in the intensive care unit: a prospective, observational study, 2017-05-02

• Esmolol infusion in patients with septic shock and tachycardia: a prospective, single-arm, feasibility study, 2018-08-03

• Modeling clinical trajectory status of critically ill COVID-19 patients over time: A method for analyzing discrete longitudinal and ordinal outcomes, 2022-01-01

• Protocols and Hospital Mortality in Critically ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study, 2015-06-03

• The reduced form of coagulation factor XI is associated with illness severity and coagulopathy in critically-ill septic patients, 2019-01-03

• Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis, 2022-08-16

• Modifiable in-hospital factors for 12-month global cognition, post-traumatic stress disorder symptoms, and depression symptoms in adults hospitalized with COVID-19, 2023-09-26

• Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?, 2014-04-08

• High Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-Like Transcript (TLT)-1 Are Associated With Acute Respiratory Distress Syndrome, 2018-05-14

• Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock, 2015-08-31

• Applying dynamic parameters to predict hemodynamic response to volume expansion in spontaneously breathing patients with septic shock, 2013-01-26

• Liberal versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial, 2018-05-10

• A simplified definition of diastolic function in sepsis, compared against standard definitions, 2019-02-20

• Defining and Predicting Severe Community-Acquired Pneumonia (SCAP), 2010-05-14

• A Modified Sequential Organ Failure Assessment (MSOFA) Score for Critical Care Triage, 2013-09-27

• Glasgow Coma Score dominates the association between admission Sequential Organ Failure Assessment score and 30-day mortality in a mixed ICU population, 2014-05-28

• Alive and Ventilator-Free: A Hierarchical, Composite Outcome for Clinical Trials in the Acute Respiratory Distress Syndrome., 2019-12-15

• Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis, 2022-09-29

• Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome, 2014-12-16

• Relationships among initial hospital triage, disease progression, and mortality in community-acquired pneumonia, 2012-07-18

• Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpatients with COVID-19 (TICO/ACTIV-3), 2021-10-10