Dr. Scott Armstrong, MD

• Pediatric Hematology & Oncology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Dana-farber/boston Children's Cancer And Blood Disorders Center

  Fellowship Hospital, 2001

• Boston Combined Residency Program (bcrp)

  Internship Hospital, 1998

• Boston Combined Residency Program In Pediatrics

  Residency Hospital, 1998

• University Of Texas Southwestern Medical Center

  Medical School, 1996

• iCanPlot: Visual Exploration of High-Throughput Omics Data Using Interactive Canvas Plotting, 2012-02-29

• Therapeutic targeting of preleukemia cells in a mouse model ofNPM1mutant acute myeloid leukemia, 2020-01-31

• Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia, 2023-03-01

• Abrogation of MLL-AF10 and CALM-AF10 mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l, 2012-11-09

• Self-renewal related signaling in myeloid leukemia stem cells, 2011-07-29

• Chromatin modifying enzymes as modulators of reprogramming, 2012-03-04

• Hedgehog Signaling Is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis, 2009-06-05

• Genetics, Epigenetics and Leukemia, 2010-11-10

• AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias, 2011-09-02

• AF10 Regulates Progressive H3K79 Methylation andHOXGene Expression in Diverse AML Subtypes, 2014-11-20

• mTOR Complex 1 Plays Critical Roles in Hematopoiesis andPten-Loss-Evoked Leukemogenesis, 2012-09-07

• Chromatin modifications as therapeutic targets in MLL-rearranged Leukemia, 2012-08-03

• A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition, 2023-01-09

• MLL-rearranged Leukemia is Dependent on Aberrant H3K79 Methylation by DOT1L, 2011-07-12

• The Wnt/ß-catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML, 2010-03-26

• Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL, 2015-02-16

• HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis, 2018-09-27

• NUP98-Fusion Proteins Interact With the NSL and MLL1 Complexes To Drive Leukemogenesis, 2016-11-23

• Antigen presentation safeguards the integrity of the hematopoietic stem cell pool, 2022-05-05

• Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression inNPM1Mutant Leukemia, 2016-08-17

• IKAROS and MENIN Coordinate Therapeutically Actionable Leukaemogenic Gene Expression in MLL-r Acute Myeloid Leukaemia, 2022-05-09

• Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition, 2020-06-30

• A Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models ofMLL-rearranged leukemia, 2019-12-09

• Pathprinting: An integrative approach to understand the functional basis of disease, 2013-07-26

• Genetic and Pharmacologic Inhibition of ß-Catenin Targets Imatinib Resistant Leukemia Stem Cells in CML, 2012-04-06

• Resistance mechanisms to SYK inhibition in acute myeloid leukemia, 2019-11-26

• Histone acetyltransferase activity of MOF is required forMLL-AF9leukemogenesis, 2017-02-15

• A novel mutation in themiR-128bgene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells, 2010-03-15

• MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape, 2022-03-03

• A non-catalytic function of SETD1A regulates Cyclin-K and the DNA damage response, 2018-02-22

• MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor, 2022-07-06

• H3K79 methylation profiles define murine and human MLL-AF4 leukemias, 2008-11-04

• MEN1mutations mediate clinical resistance to Menin inhibition, 2023-03-15

• SETD2 haploinsufficiency enhances germinal center-associated AICDA somatic hypermutation to drive B cell lymphomagenesis, 2022-07-06

• MLL-Rearranged B Lymphoblastic Leukemias Selectively Express the Immunoregulatory Carbohydrate-Binding Protein Galectin-1, 2010-03-23

• KRasG12D-evoked leukemogenesis does not require ß-catenin, 2013-11-05

• Epitope editing enables targeted immunotherapy of acute myeloid leukaemia, 2023-08-30

• Cell of origin determines clinically relevant subtypes ofMLL-rearranged AML, 2012-12-13